Comprehend different evolutionary models for genetic load and how these led to the neutral theory of molecular evolution. Understand and describe the “Neutral theory” and the “nearly neutral theory”. Know the major predictions of neutral theory and give examples where predictions have been validated with real molecular data. Comprehend both the benefits and pitfalls of neutral theory.

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Prerequiste Learning Outcomes

What the student is assumed to know before learning this outcome.

Apply the Mendelian principles of heredity for both autosomal and sex-linked inheritance. [BIOL 2030]
Compare and contrast the fundamental features of mitosis and meiosis with emphasis on the movement of homologous chromosomes during these cellular reproductive processes [BIOL 1010] [BIOL 1030]
Comprehend the basic principles of population and quantitative genetics, and give examples of their application to real biological systems. [BIOL 2030]
Define and explain the four evolutionary forces, mutation, selection, drift and migration. [BIOL 2040]
Describe and diagram the structure of DNA. [BIOL 2030]
Describe how DNA is transcribed to RNA and how RNA is translated into proteins. [BIOL 2030]
Explain the basic mechanism(s) by which evolutionarily novel characters (e.g. wings, eyes, blood clotting, flagellae) arise. [BIOL 2040]
Explain the basic process of evolution by natural selection (following from what are sometimes called Darwin's postulates). [BIOL 2040]
Interpret Mendel’s rules of heredity in terms of the eukaryotic cell cycle. Describe meitoic crossing over and its relationship to genetic linkage. [BIOL 2030]
Interpret genetic and protein variability using detailed knowledge of the genetic code and the processes of transcription and translation. [BIOL 2030]
Predict the effects of each evolutionary force on allele and genotype frequencies in a given situation and for combinations of two evolutionary forces (calculate the change for simple situations – qualitative predictions for situations involving two evolutionary forces. [BIOL 2040]

Courses Covering This Learning Outcome

BIOL 3046

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