• Develop a basic understanding and appreciation of techniques used in genetic and molecular biology laboratories.
  • Explain and illustrate the fundamental biochemistry required in the application of modern techniques of molecular biology: (i) screen complementary (cDNA) and genomic libraries to identify and clone specific DNA (gene) sequences; (ii) DNA sequencing
  • Generate and interpret data collected from experiments in the laboratory and communicate results by a variety of written forms.
  • Access the Faculty of Science Academic Integrity Module in order to be able to elaborate on Dalhousie’s policies on academic integrity and the penalties that relate to plagiarism.
  • Apply knowledge of genetics to the analysis of human pedigrees.
  • Compare and contrast the fundamental mechanisms that regulate gene expression in prokaryotic and eukaryotic cells.
  • Define in detail the classes of physical and chemical mutagens, how a chemical mutagen can be identified by the Ames test, and the effect of different types of mutation on phenotype.
  • Demonstrate ability to properly summarize, paraphrase, cite and reference scientific literature in order to avoid plagiarism.
  • Describe and diagram the structure of DNA.
  • Describe how DNA is transcribed to RNA and how RNA is translated into proteins.
  • Describe in detail restriction endonucleases, their recognition sequences in DNA, and their application in the Southern blot and hybridization technique for diagnosis of human genetic disease.
  • Describe the structure of RNA and understand how post-transcriptional processing modifies it prior to translation.
  • Diagram chromosome structure, the types of rearrangements and explain the consequences of variations in chromosomal number.
  • Explain and illustrate how DNA replication and recombination
  • Interpret genetic and protein variability using detailed knowledge of the genetic code and the processes of transcription and translation.
  • Recognize the importance of genetics to society and the study of biology, and be able to effectively explain this to non-specialists.
  • Apply the Mendelian principles of heredity for both autosomal and sex-linked inheritance.
  • Comprehend the basic principles of population and quantitative genetics, and give examples of their application to real biological systems.
  • Explain how complex genetic systems lead to modifications of the basic principles of Mendelian inheritance.
  • Interpret Mendel’s rules of heredity in terms of the eukaryotic cell cycle. Describe meitoic crossing over and its relationship to genetic linkage.
  • Apply theories and topics learned in the course by solving problems in lecture, tutorials and labs.